The high-pressure microfluidizer is a device that is used to disrupt cells and homogenize samples, obtain fine particles in the laboratory or for small-scale production. The microfluidizer is suitable for processing a wide range of materials: cells, tissues, liposomes, emulsions and suspensions. By providing improved homogenization, microfluidizers allow cells to be disrupted and intracellular components released, including enzymes, proteins and DNA.
A microfluidizer uses a pump to create high pressure to disintegrate fibers using shear forces. Fiber suspension is fed into the inlet and then forced through a Y-type or Z-type narrow channel under high pressure. This results in acceleration of the suspension that creates high shear rate and eventually breaks up the fibers.